A
ABCG1 regulated with interleukin 22,
and impairs cholesterol efflux, in macrophages, 23
ACTH, treatment for IgA nephropathy, 104
Acute endovascular reperfusion therapy, in ischemic stroke, 22
Acute lung injury, induced by LPS, with imatinib effect on vascular dysfunction, 13
Acute megakaryoblastic leukemia (AMKL), associated with t(2;8), transformed from chronic myelomonocytic leukemia, 83
Acute myeloid leukemia (AML)
impact of distance from residence to treatment outcome, analysis of, 86
pretreatment biochemical and clinical variables for, 82
Acute respiratory distress syndrome (ARDS), epigenetics and health disparities of, cytosine modifications in MYLK, in nested case-control study, 59
Adipose tissue inflammation, in obesity, comparative effectiveness of native and nanoformulated SOD on, 41
Alcoholic hepatitis, in patients with thrombocytopenia, 84
Anticoagulation and thrombophilia recognition, with atherothrombosis amelioration, 3
Anti-TNF therapy, associated with novel SNP in TNFRSF1B, in inflammatory bowel disease patients, 67
Apoptotic and stress signaling
induced by cardiotonic steroids, in first trimester cytotrophoblast cells, 21
markers expression in preeclamptic umbilical cords and placentas indicate an adverse impact on offspring, 116
Arteriovenous (AV) block, and Takostubo’s cardiomyopathy, 14
Atherothrombosis, amelioration with thrombophilia and anticoagulation recognition, 3
Atrial fibrillation treatment, with balloon catheter, 15
Atrioventricular nodal function, microrna-130a regulation of, 8
Atypical hemolytic uremic syndrome (AHUS), treated with eculizumab, 115
B
Baseline gene expression levels and in vitro drug sensitivity, for clinical drug response prediction, in cell lines, 77
B-cell non-Hodgkin lymphoma, diagnosis of, using sigmoid polyp, 71
Beta-catenin in smooth muscle cells, ineffective on pulmonary hypertension development, 123
Bilateral squamous metaplasia, of conjunctiva, side effect of risedronate sodium, 68
Biomarker, in early diabetic nephropathy, urinary exosomal ceruloplasmin for, 101
Bortezomib
reversed multiple myeloma (MM), with high index of suspicion and prompt diagnosis by plasma free light chains (PFLC), in acute kidney injury (AKI), 114
velcade induced SIADH, encephalopathy and profound hyponatremia due to, 107
Breast cancer, inflammatory and invasive of, aneuploidy for osteoprotegerin, 73
Breathe measurement, of altered tissue glucose oxidation in obese and diabetes mellitus, 43
B-type natriuretic peptide (BNP), associated with wedge pressure, in surgical intensive care unit, 17.8
C
Cancer chromosomal instability, DNA damage response during mitosis induces, 62
Caspase-1activation, inflammatory protease release from monocytes in response to endotoxin, 136
Caspase-12 deficiency, protects against bleomycin-mediated acute lung injury, 128
CC-chemokine expression, and levels of CCR5 downregulation, during coinfected HIV-1/HTLV-1/2, 87
CCR5 downregulation, and CC-chemokine expression, during coinfected HIV-1/HTLV-1/2, 87
CD4 T cell responses, long term impairment of, after sepsis, 135
CD36 transcription regulation, in endothelial cell with signaling kinase PKD-1, and arteriogenic response stimulation, 85
Cell assembly exposed to high glucose states, alterated by three dimensional cell cultures, 109
Cell senescence, associated with chromatin-mediated gene expression profile, RAP1 relocalization, 69
Cental diabetes insipidus (CDI), undiagnosed for 3 decades till unmasked by dehydration due to endotracheal intubation and stupor, 108
CGMP-dependent protein kinase I expression, with regulation of hyperglycemia, in first trimester cytotrophoblast cells, 66
Chest pain, left pectoral pyomyositis secondary to community acquired MRSA, 89
Chilaiditi syndrome, rare case presenting as chest pain, 49
Chromatin-mediated gene expression profile, associated with cell senescence pace, RAP1 relocalization, 69
Chronic house dust mite exposure, stimulates alveolar macrophages transition to regulatory phenotype, 141
Chronic kidney disease, activated omentum slows progression of, 106
Chronic myelomonocytic leukemia(CMML), associated with t(2;8), acute megakaryoblastic leukemia (AMKL) rare transformation from, 83
Cigarette smoke exposure, cause lung inflammation with altitude, 131
Clostridium difficile infection
CMV sero-status, presence of jejunostomy and use of proton pump inhibitor are associated with increased risk of, 94
in hospitalized patients with cystic fibrosis, 52
risk factors for recurrent, 90
cMYBP-C
interaction with myosin S2, 19
on pressure-overload induced hypertrophy, haploinsufficiency of, 9
COMP-Ang1, associated with diabetic retina and endothelial progenitor cells, vascular stem cell therapy of, 4
Conjunctiva, bilateral squamous metaplasia of, 68
Coxsackievirus B3 (CVB3) mediated viral myocarditis, TNNI3K over-expression exacerbates inflammation in, 6
Crohn’s disease, with EBV and CMV co-infection, diagnostic dilemma, 53
Cyclotetrapeptides synthesis, by macrolactamization methods, 63
Cystic nephroma, proliferation of, 112
D
Deep venous thrombosis-pulmonary embolus, testosterone therapy, thrombophilia, and hospitalization for, 38
Diabetes education, for pediatric residents with an online module, 46
Diabetes outcomes improvement, with peer mentoring pilot project, 48
Diabetic foot ulcers (DFU), treated with skin substitutes (SS), with wound healing influence, 95
Diabetic nephropathy, urinary exosomal ceruloplasmin biomarker of, 101
Diabetic retina, associated with COMP-Ang1 and endothelial progenitor cells, vascular stem cell therapy of, 4
Dilated cardiomyopathy, associated with oxidative stress and inflammation, in mouse model, 5
DNA damage, response during mitosis induces cancer chromosomal instability, 62
E
Eculizumab, postpartum atypical hemolytic uremic syndrome (AHUS) treated with, 115
Emergency department, in relation with clostridium difficile infection, in united states 2006–2009, 55
Endoplasmic reticulum stress, up-regulates TRIP-Br2 in visceral fat, 27
Endoscopic retrograde cholangiopancreatography (ERCP), in children, trends within United States from 2000–2009, 51
Endothelial cell migration, 5-hydroxytryptamine type 7 receptor (5-HT7R) regulated by, 18
Endothelial mesenchymal transitions (ENDMT) and vascular permeability, promoted with Kaposi’s sarcoma-associated herpesvirus (KSHV) infected cells, nanovesicles secretion in, 93
Exogenous testosterone (T) therapy, thrombotic events developed after starting, 29
Ezrin/Radixin/Moesin proteins genes expression, in pulmonary inflammation, regulation of, 133
F
Factor V Leiden heterozygosity and high factor VIII, in women with idiopathic osteonecrosis, 37
Factor V Leiden mutation (FV), associated with ocular thrombosis, 78
Familial thrombophilia (factor V leiden heterozygosity, high factor VIII), in women with idiopathic osteonecrosis, 37
Fibrinogen amyloidosis, with CNS manifestation, 110
Functional activities performance, involving pushing, role of asymmetry of posture and arm movement during, 45
G
GCK-related hyperglycemia, misdiagnosed and treated in US, 44
Gender and race difference, with gout impact, on patient’s QOL, 140
Genes expression regulation, with Ezrin/Radixin/Moesin proteins, in pulmonary inflammation, 133
Global energy metabolism, adult and developmental exposure to endocrine disruptor tolylfluanid on, 32
Glucose and lipid metabolism, sexual dimorphic impact of adult-onset hepatic gh resistance on, 39
Granulomatous-lymphoproliferative interstitial lung disease (GLILD), diagnosis of, 121
Group V phospholipase A2 gene expression, in pulmonary inflammation, regulation of, 125
Growth factors and hypoxia, sphingosine 1-phosphate receptors transcription regulation by, 2
H
Heart failure patients, with mechanical circulatory support, diabetic control improvement, 11
Hereditary hemorrhagic telangiectasia, transcatheter embolization of pulmonary arteriovenous malformation in, 12
HER2, tissue microarrays in, 80
HIV infection, rhabdomyolysis as presenting sign of, 92
Hormone therapy, followed central retinal vein occlusion, in hyperhomocysteinemia patients, 79
Human cell-free DNA (cfDNA), isolation, sequencing and analysis, 65
Human pancreatic islets, heterogeneity of secretory granule structure in, 25
5-hydroxytryptamine type 7 receptor (5-HT7R), regulates endothelial cell migration, 18
Hyperglycemia, impairs first trimester cytotrophoblast function and induces anti-angiogenic milieu via stress signaling, 36
Hyperhomocysteinemia, hormone therapy followed central retinal vein occlusion in, 79
Hypoxia, induces the stress and apoptotic signaling in cultured rat lung microvascular endothelial cells, 126
I
Idiopathic osteonecrosis, medical treatment of, 72
Idiopathic sudden sensorineural hearing loss (ISSHL), with previously undiagnosed thrombophilia, 26
IFN induction by influenza, through RIG-I AND TLR3 signaling, in human lung epithelia, 132
IgA nephropathy, ACTH treatment for, 104
Imatinib treatment, associated with MRNA and microrna signature, in chronic myeloid leukemia cell line, 57
Inflammatory bowel disease, patients with SNP in TNFRSF1B associated with anti-TNF therapy, 67
Inflammatory breast cancer (IBC), and invasive breast cancer aneuploidy, osteoprotegerin in, 73
Integrated multivariable artificial pancreas control systems work and operator controlled systems, 40
Intestinal epithelial cells, with oxalate transport regulates proinflammatory cytokines, 105
Ischemic stroke, acute endovascular reperfusion therapy in, 22
J
JAK-2 V617F positive polycythemia vera, erlotinib ineffective in patients (pts), 75
K
Kaposi’s sarcoma-associated herpesvirus (KSHV)
infected cells promote endothelial mesenchymal transitions (ENDMT) and vascular permeability, nanovesicles secretion in, 93
latency monocyte recruitment and lipogenesis, induced 5-lipoxygenase-leukotriene B4 (5LO/LTB4) cascade, roles in, 91
Kaposi’s sarcoma tumor cells, role of lipoxins in, 97
Kidney biopsy, of quiescent lupus nephritis, 100
Knee, idiopathic osteonecrosis of, 72
L
Lipid-associated microbiome, immunoregulatory role in multiple sclerosis, 138
Lipoxins, in Kaposi’s sarcoma tumor cells, 97
Liver function tests and occurrence of anemia, thrombocytopenia and leucopenia- retrospective cohort study, 50
Long term anticoagulation, stops progression of osteonecrosis in patients heterozygous for the factor V leiden mutation, 70
LPS-induced lung injury, epigenetic regulation of, by sphingosine-1-phosphate lyase, 127
Lupus nephritis, molecular characterization of renal responses in, using serial kidney biopsies, 111
M
Macrolactamization methods, for cyclotetrapeptides synthesis, 63
MAPK8, expression quantitative trait locus with pre-capillary pulmonary hypertension in sickle cell disease, 60
Metastatic chromophobe renal cell carcinoma (MET CH RCC), using axitinib, treatment of, 81
Microrna-130a regulation, of atrioventricular nodal function, 8
MRNA and microrna signature, in response to imatinib treatment, in chronic myeloid leukemia cell line, 57
Multidimensional health assessment questionnaire, in systemic lupus erythematosus, measurement properties of, 139
Multiple myeloma (MM) reversed by bortezomib, acute kidney injury (AKI) due to, with high index of suspicion and prompt diagnosis by plasma free light chains (PFLC), 114
Multiple sclerosis (MS), microbiome-associated lipid, immunoregulatory role in, 138
MYLK variant, regulates asthmatic inflammation via alterations in messenger RNA secondary structure, 122
Myosin Binding Protein-C (MyBP-C), cardiac and skeletal muscle function regulated by, 20
Myosin S2, interaction with cMYBP-C, 19
Myxedema coma, precipitated by a combination of iodinated contrast, amiodarone and calcium acetate, 28
N
Neonatal diabetes, sulfonylurea treatment before genetic testing in, 31
Nephropathy, urinary exosomal ceruloplasmin biomarker of, in early diabetic, 101
NLRP3, inflammasome reduces severity of experimentally-induced acute pancreatitis, 35
O
Obese and diabetes mellitus, breathe measurement of altered tissue glucose oxidation in, 43
Obesity, comparative effectiveness of native and nanoformulated SOD on adipose tissue inflammation in, 41
Ocular thrombosis, of previously undiagnosed factor V leiden heterozygosity, 78
Osteonecrosis progression, stops long term anticoagulation, in patients heterozygous for the factor V leiden mutation, 70
P
P. aeruginosa epigenetic regulation, mediated acute lung injury by spingosine kinase 2, 118
PBEF/NAMPT gene expression, with epigenetic regulation of hsa-miR-374a and hsa-miR-568, in human lung endothelium, 61
Pdx1-Cre;KrasG12D/+ cohort, sequestration of oxidized lipids, immunomodulation, and tumor progression in, 74
Pityriasis rubra pilaris, treated with ustekinumab, 134
Placental expression, of renin-angiotensin system components and (PRO)renin receptor in preeclamptic pregnancy, 102
Post-operative insulin resistance, predicts diabetes medications at discharge post liver transplant, 30
Pre-adipocyte factor-1 (PREF-1), correlates with decreased body fat, increased free fatty acids, and the levels of recent alcohol consumption in excessive alcohol drinkers, 54
Preeclampsia
placental expression of renin-angiotensin system components and (PRO)renin receptor in preeclamptic pregnancy, 102
urinary angiotensinogen excretion reduction in, 103
Pulmonary arterial compliance (PAC), in relation with pulmonary vascular resistance, in mechanically ventilated critically ill surgical patients, 7
Pulmonary arteriovenous malformation,1 transcatheter embolization of, in hereditary hemorrhagic telangiectasia, 12
Pulmonary endothelial barrier, enhanced by FTY720 S-phosphonate, mediated by junctional complex and focal adhesion rearrangement, 119
Pulmonary fibrosis, with endogenous suppressor of sphingosine 1 phosphate lyase, in human and mouse model, 129
Pulmonary hypertension development, ineffective with beta-catenin delection, in smooth muscle cells, 123
Pulmonary inflammation, group V phospholipase A2 gene expression regulation in, 125
Pulmonary insufficiency, of unknown etiology, 76
Pulmonary vascular resistance (PVR), in relation with pulmonary arterial compliance, in mechanically ventilated critically ill surgical patients, 7
Q
Quiescent lupus nephritis, kidney biopsy of, 100
R
Radiation nephropathy, with epoxyeicosatrienoic acid analog mitigator, 113
Receptor tyrosine kinase, in glioblastoma mediates resistance to PDGFR inhibition, 56
Renal cell carcinoma (RCC), of metastatic chromophobe, using axitinib, treatment of, 81
Renal responses in lupus nephritis, molecular characterization of, using serial kidney biopsies, 111
Resident led initiative to provide real time feedback, patient satisfaction improvement, 47
Rhabdomyolysis, as presenting sign of HIV infection, 92
Risedronate sodium, bilateral squamous metaplasia of conjunctiva, side effect of, 68
RNA-Seq, data analysis from lung biopsy and peripheral blood mononuclear cells of an idiopathic pulmonary fibrosis patient, 58
Roux en Y gastric bypass (RYGB), postprandial response to altered feeding routes and reversal surgery in, 34
S
Secondary pulmonary emboli, associated with previously undiagnosed familial thrombophilia, 76
Sepsis-induced ARDS, gene expression profiling of non-injurious mechanical ventilation in an animal model of, 124
Severe alcoholic hepatitis, in patients with thrombocytopenia, 84
Severe sepsis-induced acute respiratory distress syndrome, associated with functional promoter of sphingosine 1-phosphate receptor 1, 117
SIADH induced by bortezomib (velcade), encephalopathy and profound hyponatremia due to, 107
Sickle cell disease, house dust mite-induced allergic airway disease associated with reduced regulatory immune cells and increased pathology, in murine model, 137
Single nucleotide polymorphisms (SNPs), of CYP2C9 and VKORC1, in association with S-warfarin clearance, in African Americans, 24
Solid organ transplant (SOT), Clostridium difficile infection risk after, 94
Soluble receptor of advanced glycation endproducts (sRAGE), is decreased across glucose tolerance continuum and correlates with severity of insulin resistance, 33
Sphingosine-1-phosphate lyase, in LPS-induced lung injury, epigenetic regulation of, 127
Sphingosine 1-phosphate receptor, transcription regulation of, by growth factors and hypoxia, 2
Sphingosine 1-phosphate receptor 1 functional promoter, associated with severe sepsis-induced acute respiratory distress syndrome, 117
Spingosine kinase 2, epigenetic regulation of P. aeruginosa mediated acute lung injury by, 120
STAT6, alters JMJD3-dependent M2 macrophage differentiation in pulmonary fibrosis, 130
Stathmin, expression is more reliable than p16 protein, as a marker for high-grade cervical and laryngeal dysplasias, 64
Stress and apoptotic signaling, induced by cardiotonic steroids, in first trimester cytotrophoblast cells, 21
Sulfonylurea, treatment before genetic testing in neonatal diabetes, 31
S-warfarin clearance, in association with CYP2C9 and VKORC1 SNPS, in African Americans, 24
Systemic lupus erythematosus
isolated by divergent genome-wide transcriptional profiles, from immune cell subsets, 143
measurement properties of, multidimensional health assessment questionnaire in, 139
T
Takostubo’s cardiomyopathy, AV block and, 14
Thrombophilia and anticoagulation recognition, with atherothrombosis amelioration, 3
Thrombotic events, developed after starting exogenous testosterone (T) therapy, 29
Tissue microarrays, in HER2 immunohistochemical assay for guiding clinical treatment, 80
TNNI3K, over-expression exacerbates inflammation, in coxsackievirus B3 (CVB3) mediated viral myocarditis, 6
Transcatheter embolization, of pulmonary arteriovenous malformation in, hereditary hemorrhagic telangiectasia, 12
Transcription regulation, of sphingosine 1-phosphate receptors, by growth factors and hypoxia, 2
TRIP-Br2, up-regulated by endoplasmic reticulum stress in visceral fat, 27
U
Urate-lowering therapy (ULT), adherence with gout, facilitators and barriers in African-Americans, 142
Uremic frost, histologic findings and diagnosis of, 99
Urinary angiotensinogen excretion, reduction in preeclampsia, 103
Ustekinumab, pityriasis rubra pilaris treated with, 134
V
Vaginal microbiome, vitamin D supplementation in, bacterial vaginosis and, 96
Vascular dysfunction, in LPS-induced acute lung injury, imatinib, 13
Viral myocarditis, over-expression of TNNI3K, a cardiac specific kinase, exacerbates inflammation in coxsackievirus B3 (CVB3) mediated, 6
Vitamin D
role in preventing leaky gut-induced endotoxemia in subjects at risk for diabetes, 42
supplementation, in bacterial vaginosis and vaginal microbiome, 96
W
Wound healing, influence diabetic foot ulcers (DFU), treated with skin substitutes (SS), 95