High risk >3% annual mortality rate | 1. Severe resting left ventricular dysfunction (LV EF < 35%) |
2. High-risk treadmill score (score ≤−11) |
3. Severe exercise LV dysfunction (exercise LV EF <35%) |
4. Stress-induced large perfusion defect (particularly if anterior) |
5. Stress-induced multiple perfusion defects of moderate size |
6. Large, fixed perfusion defect with LV dilation or increased lung uptake (thallium-201) |
7. Echocardiographic wall motion abnormality (involving >2 segments) developing at a low dose of dobutamine (≤10 mg/kg/min) or at a low heart rate (<120 bpm) |
8. Stress echocardiographic evidence of extensive ischemia |
Intermediate risk 1–3% annual mortality rate | 1. Mild/moderate resting LV dysfunction (LV EF=35–49%) |
2. Intermediate-risk treadmill score (−11 < score < 5) |
3. Stress-induced moderate perfusion defect without LV dilation or increased lung intake (thallium-201) |
4. Limited stress echocardiographic ischemia with a wall motion abnormality only at higher doses of dobutamine involving ≤2 segments |
Low risk <1% annual mortality rate | 1. Low-risk treadmill score (score ≥5) |
2. Normal or small myocardial perfusion defect at rest or with stress |
3. Normal stress echocardiographic wall motion or no change in limited resting wall motion abnormalities during stress |